CD52 and B-cell chronic lymphocytic leukemia: Moreover, while CD52+MVs did not show any association with Rai-risk in CLL patients, their increased levels were reported in high FISH-risk (17p-/11q-) as compared to low FISH-risk (13q-/Tri12 or no genetic abnormalities) patients, thus indicating that further studies are needed to better establish CD52+MV role as prognostic marker in this disease.