Given this, we have recently investigated the pattern of association of 95 prioritized SNPs of the GWAS identified SNPs in the 11q23.3 region9,10 in the CAD patients from Hyderabad, India11,12 and observed significant association of 12 SNPs in the intronic regions of APOA1, BUD13, ZPR1 and the intergenic region of APOA5-APOA4 genes with distinct effects towards CAD and dyslipidemia. This evidence concerns the gene APOA1 and coronary artery disorder.