There were 97 subjects in the PKG+ arm (assessment of PD made using clinical evaluation as well as with access to PKG information) and 103 in the PKG− arm (assessment of PD made using only clinical evaluation) and 46 were withdrawn during the study: 7 for protocol violations, 11 referred for device-assisted therapy and the remainder were participant-initiated withdrawal for social, personal or non-PD medical reasons. This evidence concerns the gene PRKG1 and Parkinson disease.