GBA1 and glycogen storage disease VI: In addition, the dopamine quinone has also been shown to interact with Parkinson’s disease-associated chaperone protein DJ-1, and dopamine and its metabolic products have also been shown to interact with α-synuclein, which can cause downstream deficits in chaperone mediated autophagy, decreased glucocerebrosidase activity, damage to synaptic vesicles, and mitochondrial dysfunction9,10,50–57.