Histological analysis revealed reduced tumor foci in the spleens and LNs of tamoxifen-treated MycEμCreERT2Trib3F/+ mice compared to lymphoma-matched vehicle recipients (Fig. 1l), which was caused by the tamoxifen-induced loss of TRIB3 in lymphoma tissues (Supplementary Fig. 1j). This evidence concerns the gene TRIB3 and neoplasm.