Thus, the expression of desmoplakin, one of the desmosomes, was analyzed, and loss of desmoplakin expression was found in DKO cells and mesothelioma cell lines, providing further experimental evidence for the EMT phenotype45; therefore, we propose that CD24 expression induces the EMT phenotypes involved in the pathogenesis of MPM. The gene discussed is DSP; the disease is mesothelioma.