Through conducting caspase 3/8/9 activity detection and TUNEL assay, we certified the facilitative effect of ETS1 knockdown on glioma cell apoptosis, while such impact was then rescued by SNHG10 up-regulation, miR-532-3p repression or FBXL19 overexpression (Additional file 3: Fig. S3C, D). Here, FBXL19 is linked to central nervous system cancer.