To know the impact of SNHG10 on glioma cell functions, SNHG10 expression was silenced or up-regulated in U138 and U251 cells through separately transfecting sh-SNHG10#1/2 or pcDNA3.1/SNHG10 (Additional file 1: Fig. S1A, B). The gene discussed is SNHG10; the disease is central nervous system cancer.