Finally, seen from the results of wound healing and transwell assays, we knew that the hampered migration and invasion of glioma cells with ETS1 deficiency was recovered after further overexpressing SNHG10, inhibiting miR-532-3p or up-regulating FBXL19 (Additional file 4: Fig. S4C, D). The gene discussed is FBXL19; the disease is glioma.