An admission Cr/Alb cut-off ≥ 3.43 could predict worse prognoses in AP patients, including a more severe heart rate and respiratory rate, impaired levels of blood urea nitrogen, Cr, Alb, white blood cells and platelets, APACHE II score, post-operative electrolyte disorders, respiratory failure, hemorrhage, shock, renal failure, re-operation rate, and mortality. The gene discussed is ALB; the disease is respiratory failure.