The majority of patients suffer from sporadic ALS (sALS; >90%), while only a small subset of patients suffers from inherited ALS (fALS; <10%) 20% of cases have been linked to mutations in the gene encoding copper-zinc superoxide dismutase (SOD1) [4], which represent the 2% of all cases of fALS. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.