Four drugs have been recently approved by the FDA for that purpose [474], the potentiator Ivacaftor (VX-770) for individuals with CF holding a G551D CFTR mutation, and the following three correctors: Lumacaftor (VX-809), developed to increase the amount of F508del CFTR that reaches the cell surface [478,479], Tezacaftor (VX-661), and Elexacaftor (VX-445). Here, CFTR is linked to cystic fibrosis.