It has been shown that the overexpression of miR-888-5p significantly increases the proliferation and migration of prostate cancer cells [43] and hepatocellular carcinoma, where it promoted cancer growth by decreasing p53 level and induced migration and invasion by targeting SMAD4, leading to the modulation of the main EMT markers [46]. The gene discussed is SMAD4; the disease is hepatocellular carcinoma.