SLC1A2 and Parkinson disease: Recently, Sheng et al. [142] provided a new perspective on the pathogenesis of PD; erythrocyte-derived α-synuclein in extracellular vesicles was found to readily cross the BBB and accumulate in astrocyte end-feet, where they impaired glutamate uptake, likely via interaction between EAAT2 and oligomeric α-synuclein.