Statistically significant lower abundance of both ISL1 and NEFH and higher abundance of both RPS2 and RAB13 were observed commonly in 201B7 iPSC‐derived motor neurons and ALS patient‐derived motor neurons harboring mutated TDP‐43 at G298S (Fig. 4B,C). Here, RPS2 is linked to amyotrophic lateral sclerosis.