Additional workup revealed adrenal nodular hyperplasia, elevated 17-hydroxyprogesterone (19 910 ng/dL) and dehydroepiandrosterone sulfate (378 mcg/dL), and 2 mutations of the <i>CYP21A2</i> gene consistent with simple virilizing CAH. This evidence concerns the gene CYP21A2 and congenital adrenal hyperplasia.