Despite unavailable analysis for the correlations between S100A7A, S100A7L2, and S100G expressions and OS or DFS of CRC patients due to insufficient data, the analysis for the other S100 genes revealed that the S100A1 overexpression was associated with worse OS of patients with COAD and READ (p < 0.05) (see Figure 5) and that S100A2~S100A14, S100A16, S100B, S100P, and S100Z expressions had no significant correlations with OS of the patients. The gene discussed is S100A2; the disease is colon adenocarcinoma.