An omics study revealed that SOX2-OT interacted with 6 differentially expressed miRNAs (hsa-mir-192-5p, hsa-mir-215-5p, hsa-mir-204-5p, hsa-mir-205-5p, hsa-mir-338-3p, hsa-mir-375) among 96 esophageal squamous cell carcinoma samples and 13 normal tissue samples [23]. This evidence concerns the gene SOX2 and esophageal squamous cell carcinoma.