A lncRNA PCR array containing 90 common lncRNAs in peripheral blood mononuclear cells from patients with multiple sclerosis revealed a group of dysregulated lncRNAs in multiple sclerosis patients, and SOX2-OT was one of the most strongly downregulated lncRNAs with p < 0.001 [50]. The gene discussed is SOX2; the disease is multiple sclerosis.