Network pharmacology analysis showed that 20 target genes were regulated by GQD in CRC, including PTGS2, CCNB1, SPP1, PLAU, MAOA, OLR1, NR3C2, HSD3B2, TNFSF15, AKR1C3, CA2, MMP1, MMP3, MMP9, IL1B, DUOX2, ABCG2, CXCL11, CXCL10, and ADH1C. This evidence concerns the gene CA2 and colorectal carcinoma.