SPP1 and colorectal carcinoma: Twenty CRC-specific GQD-target genes are displayed as V-shaped polygons in blue, including PTGS2, OLR1, NR3C2, HSD3B2, TNFSF15, MMP1, MMP3, MMP9, AKR1C3, CA2, PLAU, IL1B, DUOX2, CCNB1, ABCG2, CXCL11, CXCL10, SPP1, ADH1C, and MAOA.