Twenty CRC-specific GQD-target genes are displayed as V-shaped polygons in blue, including PTGS2, OLR1, NR3C2, HSD3B2, TNFSF15, MMP1, MMP3, MMP9, AKR1C3, CA2, PLAU, IL1B, DUOX2, CCNB1, ABCG2, CXCL11, CXCL10, SPP1, ADH1C, and MAOA. Here, AKR1C3 is linked to colorectal carcinoma.