The administration of streptozotocin-/nicotinamide-induced diabetes is responsible of an increase rate of proinflammatory cytokines such as TNF-α (Figure 4(a)), IL-1β (Figure 4(b)), and IL-6 (Figure 4(c)) by 76.81%, 22.27%, and 32.04, respectively, while the increase rate of the anti-inflammatory factor IL-10 was 58.41% (Figure 4(d)) as compared to normal control. This evidence concerns the gene TNF and diabetes mellitus.