We next performed enrichment analysis for the top genes that are enriched from the DA microbes on day 8 to find they are enriched for the genes known to be involved in the pathogenesis of IBD curated in KEGG pathway, along with other pathways essential for immune responses such as Jak-STAT signaling pathway, cytokine-cytokine receptor interaction as well as immune dysregulation disorders such as asthma and autoimmune thyroid disease (Table 4, Fig. 5). Here, SOAT1 is linked to autoimmune thyroid disease.