To investigate the functional importance of UBR5 in OC development and metastasis, we used a syngeneic murine OC model with ID8 cells expressing Muc16ecto (herein simply referred to as ID8), a glycoprotein upregulated in the majority of ovarian carcinomas and used as a serum biomarker for OC20. The gene discussed is UBR5; the disease is ovarian carcinoma.