MITF and melanoma: Chromatin immunoprecipitation (ChIP) sequence analysis of melanoma cells indicates that MITF potentially binds between 12,000 and 100,000 genomic sites and that ~9400 of those lie within 20 kb of an annotated RefSeq gene, but genes may not obviously exhibit MITF regulation even though they have high levels of MITF occupancy at their promoter [22, 24].