To evaluate the contribution of HIV-1 Vpr protein to the observed upregulation of proinflammatory markers and Sur1-Trpm4 in astroglial cells, we delivered the vpr gene using an adenoviral (Adv) system to a glioblastoma SNB19 cell line (RRID:CVCL_0535 from NCI) with increasing multiplicity of infection (MOI). This evidence concerns the gene ABCC8 and glioblastoma.