NPPB and heart failure: Over a follow-up period of 8 weeks, S/V, compared to enalapril, resulted in a greater reduction in NT-proBNP (− 46.7% vs − 25.3%; ratio of change 0.71 [95% CI, 0.63–0.81]) and greater reduction in hospitalization for heart failure (8.0% vs 13.8%; HR, 0.56 [95% CI, 0.37–0.84]).