m6A-modified circNSUN2 increased the cytoplasmic output, and circNSUN2 enhanced the stability of HMGA2 mRNA by forming the RNA-protein ternary complex of circNSUN2 / IGF2BP2 / HMGA2 in the cytoplasm, which promotes CRC metastasis process [92]. Here, HMGA2 is linked to colorectal carcinoma.