In the investigation of Davide Degli Esposti et al., 5525 lncRNAs from different tissues were detected to associate with that in TGF-β and 57 of them differentially expressed in HCC compared with adjacent non-tumor tissues, These lncRNAs were co-expressed with genes about liver metabolism and cell cycle [84]. The gene discussed is TGFB1; the disease is hepatocellular carcinoma.