BZRAP1-AS1 facilitates tumor angiogenesis via inducing methylation of the thrombospondin-1 (THBS1) promoter and repressing its transcription [68].Linc-GALH was observed to promote HCC metastasis through controlling the methylation status of Gankyrin, which was associated with ubiquitination of DNA methyltransferases 1 (DNMT1) [69]. The gene discussed is DNMT1; the disease is hepatocellular carcinoma.