This PTCL entity had the least abnormal genome [2], and is quite well-defined with unique clinical characteristics, pathological features and aberrant oncogenic pathways including the NF-κB pathway, IL-6 signaling, and the TGF-β pathway that have been identified to be enriched in AITL [30]. Here, NFKB1 is linked to angioimmunoblastic T-cell lymphoma.