SERPING1 and hereditary angioedema with C1Inh deficiency: Nine mutations in the SERPING1 gene were identified in nine probands with HAE-1: c.44delT, c.289C<T, c.296_303delCCATCCAA, c.538C<T, c.786_787insT, c.794G<A, c.939delT, c.1214_1223delCCAGCCAGGA, and c.1279delC (Table 1) which led to a premature stop codon in the mutation site or downstream of the mutation site.