Furthermore, LEF1-AS1 also has been proven to be positively correlated with lymph node metastasis and advanced stage during ovarian cancer progression, and enhanced LEF1-AS1 expression may predict a poor prognosis [26]. Nevertheless, the role of LEF1-AS1 and the underlying mechanism by which it functions in AIPC progression as remained unclear. Here, LEF1 is linked to metastatic malignant neoplasm in the lymph nodes.