Besides, The analysis of TCGA RNA-seq data using the TIMER database showed that ZBTB7A mRNA expression was also markedly downregulated in BLCA (bladder urothelial carcinoma), COAD (colon adenocarcinoma), LUAD (lung adenocarcinoma), READ (rectum adenocarcinoma) tissues in compared with the corresponding normal tissues (Fig. 1f). The gene discussed is ZBTB7A; the disease is rectum adenocarcinoma.