Otherwise, ZBTB7A CNV has significant correlations with infiltrating levels of B cell in 5 cancer types (BRCA, LUAD, COAD, HNSC-HPV pos, and HNSC-HPV neg), CD8 + T cells in 4 cancer types (BRCA, COAD, HNSC-HPV pos, and HNSC-HPV neg), CD4 + T cells in 2 cancer types (BLCA and BRCA), macrophages in 4 cancer types (BLCA, BRCA, LUAD, and HNSC-HPV neg), neutrophils in 6 cancer types (BRCA, CHOL, LUAD, READ, COAD, and HNSC-HPV neg), dendritic cells in 3 cancer types (LUAD, COAD, and HNSC-HPV neg) (Additional file 4: Fig. S4). This evidence concerns the gene CD4 and cancer.