Decreased expression of miR-206 was found in rhabdomyosarcoma [26], lung cancer [28], ER + breast cancer [29, 30], renal cell carcinoma [31], ER alpha + endometrioid adenocarcinoma [32], hepatocellular carcinoma [33, 34] and glioma [35]. This evidence concerns the gene ESR1 and hepatocellular carcinoma.