Putative targets for YFJP treatment of HCC were screened, from which 12 key targets (TP53, EGFR, EGF, CCND1, JUN, AKT1, IL6, MAPK1, VEGFA, ESR1, CASP3, and PTGS2) were obtained (Fig. 7a). This evidence concerns the gene PTGS2 and hepatocellular carcinoma.