For example, PKM2 promotes tumor growth and suppresses cell apoptosis through regulating Bcl-xL transcription in gastric cancer cells [40] or regulating NF-κB/p65 and HIF-1α activation [18] and mitogen-activated protein kinases (MAPKs) [41] in pancreatic tumor cells. The gene discussed is PKM; the disease is pancreatic neoplasm.