Osteoclasts are also a predominant source of a number of factors that induce MM PC migration in in vitro assays, including CCL3 [87,89], the CCR2 ligands CCL2, CCL7 (also known as monocyte chemotactic protein-3 [MCP-3]) and CCL8 (also known as monocyte chemotactic protein-2 [MCP-2]) [87,90] and the CXCR3 ligand CXCL10 (also known as interferon gamma-induced protein 10 [IP-10]) [76,91,92]. Here, CCL8 is linked to Miyoshi myopathy.