Accumulating evidence implicates growth hormone (GH) in the development and progression of a wide range of malignancies [1,2,3,4,5,6,7], including breast [8,9,10,11,12,13,14,15], prostate [16,17], colorectal [18,19], glioma [20], pancreatic [21], thyroid [22], liver [23] and endometrial cancers [24,25]. The gene discussed is GH1; the disease is glioma.