KDM6A and lung adenocarcinoma: Two histone lysine modification enzymes, such as MLL4 (13.9% vs. 46.9%, p = 0.018) and UTX (32.4% vs. 70.6%, p = 0.003), showed increased immunoreactivity in BM compared with lung adenocarcinoma, indicating that the expression of MLL4 and UTX was increased in BM (Table 2).