TWIST1 and lung adenocarcinoma: In lung adenocarcinoma samples, univariate analysis showed that the high immunoreactivity of two epithelial markers, E-cadherin (hazard ratio (HR), 4.32; 95% confidence interval (CI), 2.46–6.18) and desmoplakin (HR, 3.94; 95% CI, 2.22–5.67); one mesenchymal marker, vimentin (HR, 0.46; 95% CI, 0.25–0.67); and three EMT-TFs, Slug (HR, 0.69; 95% CI, 0.42–0.95), Twist (HR, 0.53; 95% CI, 0.24–0.83) and ZEB1 (HR, 0.59; 95% CI, 0.31–0.88), were associated with longer survival (Table 4).