CD28 and Esophageal atresia: Regarding the distribution of these receptors in the cells on non-EA donors and EA patients at baseline by fluorescence intensity and orthogonal view, VPAC1 appeared both in plasma membrane and nuclear localization in resting CD4+CD28− or CD4+CD28+ cells from both groups (Figure 6), whereas VPAC2 receptor is limited to plasma membrane in all cases studies.