TGFB1 and cancer: Signaling pathways (including TGFβ, FoxO, regulating the pluripotency of stem cells, PI3K-Akt, Hippo, HIF-1, mTOR, and Wnt), cellular process pathways (including circadian rhythm, focal adhesion, regulation of actin cytoskeleton, cell cycle, and oocyte meiosis), and pathways in cancer were among the significant pathways enriched in the target genes (Supplementary Table S3).