In a burn wound model, a bivalent vaccine composed of type-b FliC and PilA elicited robust cellular and humoral responses (consisting of a Th2 response with high levels of subtype IgG1 and lower levels of IgG2a and cytokine response of IL-4, INF and IL-17), and proved quite protective, with a 3 to 4 log reduction in bacterial load in the sites of infection within 24 h of challenge [140]. Here, HIVEP2-DT is linked to infection.