Among them, we found genes involved in epidermal KC differentiation (RORA, CLDN1, FOS, NOTCH2), control of cell cycle (WEE1, RICTOR) and lipid metabolism (ALDH3a2, DEGS1) and transcription factors (FOS, ZNF652, ZNF273, LCORL, SOX6, NFAT5), all genes involved in cellular processes known to be compromised in psoriasis. The gene discussed is CALCA; the disease is psoriasis.