IARS1 and vulvar carcinoma: The LDOC1 staining process in the cytoplasm resulted in a weak color reaction in 27.6% of the vulvar carcinoma tissue sections (IRS 1–2) (Figure 1a), 52.7% showed a moderate color reaction (IRS 3, 4, 6), and 9.5% of the specimens showed a strong color reaction (IRS 8, 12).