ACTA1 and neoplasm: CAFs are identified by several cellular markers including α-smooth muscle actin (αSMA), S100A4/fibroblast specific protein 1 (FSP-1), fibroblast activation protein (FAP), tenascin-C, periostin, desmin, platelet-derived growth factor (PDGFR)-α, PDGFR-β, Thy-1, podoplanin, integrin β1, caveolin-1, collagen 11-α1, microfibrillar-associated protein 5, and asporin, which are present in different combinations across tumor types [35,36,37,38].