Similarly, KDM6B has also been associated with the direct activation of the EMT-TF gene SNAI1, or SNAI2, in different cancer models (breast cancer cells [28], hepatocarcinoma cells [20], and CRCCs [19]) but KDM6B might also be recruited on specific promoters involved in downstream EMT signaling. Here, SNAI1 is linked to breast carcinoma.