Gao et al. [103] have found that MALTAT1 is involved in type 1 IFN-mediated SLE by up-regulating OAS2, OAS3, and OASL, confirming further the report by Ye et al. [104] claiming that full high-throughput sequencing analysis of lncRNA expression profile in SLE-PBMCs could reveal a robust “IFN signature”. The gene discussed is OAS3; the disease is systemic lupus erythematosus.