Among KUL01+ cells, there was a subset of KUL01+ cells upregulated MHC-II and CD11c expression in the spleen and lung from H7N9-infected chicken in terms of the percentage and mean fluorescence intensity (MFI) (Figure 4C,D), resembling the maturation of monocyte-derived dendritic cells observed in murine infection model [35]. The gene discussed is ITGAX; the disease is infection.