Here, our acquired data showed that ectopic expression of FOXM1 not only promoted drug-resistance to oxaliplatin and vincristine in HCT-8 cells but also increased the metastatic potential, while knockdown of FOXM1 impaired drug-resistance and metastasis in HCT-8/L-OHP and HCT-8/VCR cells (Figure 1G–1Q), suggesting that FOXM1 could drive both metastasis and chemoresistance of CRC. Here, FOXM1 is linked to colorectal carcinoma.