PLOD1 and hypogonadism: Therefore, we aimed to estimate the prevalence of true hypogonadism (clinical and biochemical) in HIV-infected males complaining about sexual symptoms, using different and gradually more specific biochemical criteria, to classify hypogonadism according to gonadotropin levels and evaluate the rate of misdiagnosis resulting from the use of TT alone versus a complete hormonal profile, including cFT and LH measurement.