On the other side, we have proven that AXT may have anti-inflammatory properties (decreased ICAM-1 overexpression) compatible with a possible beneficial effects of this compound on endothelium, including an improvement of lipid profile on the glucose metabolism in patients with hypercholesterolemia [26] and the possible prevention of age-related inflammatory diseases [27]. Here, ICAM1 is linked to familial hypercholesterolemia.