AFP and neoplasm: To further analyze the correlation of clinical features or SNRPB levels with the overall survival of HCC patients, we performed a univariate Cox regression analysis and found that higher SNRPB expression (P < 0.001), peripheral organ infiltration (P < 0.001), high AFP level (P < 0.001) and tumor embolus (P < 0.001) were associated with the poor HCC patient prognosis (Supplementary Figure 1A).