Hence, we analyzed TCGA database and showed that SNRPB expression levels were positively correlated with most well-recognized markers of cell stemness (such as CD133, EPCAM, CK19 and AFP) and negatively correlated with markers of hepatocyte epithelial cells (including ALB and TTR) in HCC (Figure 4A). The gene discussed is PROM1; the disease is hepatocellular carcinoma.