Furthermore, thrombocytopenia (i.e., PLT < 100 × 109/l) combined with high AFP levels (AFP > 8 ng/ml) resulted in a significantly increased risk of liver fibrosis (OR = 11.216) and represents an easy-to-use method to help clinicians identify more patients at higher risk for liver fibrosis, especially among outpatients. This evidence concerns the gene AFP and Thrombocytopenia.