The most recent mendelian randomization analysis including 13 781 individuals from the Lp(a)‐GWAS‐Consortium from five primarily population‐based studies and 20 793 CHD cases and 27 540 controls from a subsample of the CHD Exome+ consortium estimated a required reduction in Lp(a) effect size of 65.7 mg/dL to reach the same effect as a 1 mmol/L lowering of LDL‐C.37 This evidence concerns the gene LPA and coronary artery disorder.